android { defaultConfig { // ... multiDexEnabled true } // ... } dependencies { // ... implementation 'androidx.multidex:multidex:2.0.1' // ... } public class MyApplication extends MultiDexApplication { // ... } <application android:name=".MyApplication" // ... </application> public class MyApplication extends MultiDexApplication { @Override protected void attachBaseContext(Context base) { super.attachBaseContext(base); MultiDex.install(this); } // ... } -keep class android.support.multidex.MultiDexExtractor{*;} -keep class android.support.multidex.MultiDexClassLoader{*;}